Plant Based Bioreactors of Recombinant Cytokines (Review)
نویسندگان
چکیده
منابع مشابه
Plant seeds as bioreactors for recombinant protein production.
Plants are attractive expression systems for the economic production of recombinant proteins. Among the different plant-based systems, plant seed is the leading platform and holds several advantages such as high protein yields and stable storage of target proteins. Significant advances in using seeds as bioreactors have occurred in the past decade, which include the first commercialized plant-d...
متن کاملPlant bioreactors for pharmaceuticals.
Plant bioreactors are attractive expression systems for economic production of pharmaceuticals. Various plant expression systems or platforms have been tested with certain degrees of success over the past years. However, further development and improvement are needed for more effective plant bioreactors. In this review we first summarize recent progress in various plant bioreactor expression sy...
متن کاملOral presentations O6.1 Plant bioreactors — in and ex situ production of recombinant proteins
In the past decade, accomplishments in biochemistry and molecular biology and genetics enabled scientists not only to gather a large amount of experimental data on structural and functional organization of genomes and metabolomes but also to develop tools for manipulation and highly specific modification of the gene expression in Eukaryota, including higher plant species. Development of genetic...
متن کاملRecombinant Cytokines from Plants
Plant-based platforms have been successfully applied for the last two decades for the efficient production of pharmaceutical proteins. The number of commercialized products biomanufactured in plants is, however, rather discouraging. Cytokines are small glycosylated polypeptides used in the treatment of cancer, immune disorders and various other related diseases. Because the clinical use of cyto...
متن کاملPlants as Bioreactors- A Review
Ever since the discovery of genetic manipulation and the establishment of various methods for effective transformation of cells, the use of plants as an expression system for the production of recombinant therapeutic proteins have been advocated. This has been an exciting as well as controversial concept. Plants produce large biomass hence plants can produce large quantities of recombinant prot...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Applied Biochemistry and Microbiology
سال: 2016
ISSN: 0003-6838,1608-3024
DOI: 10.1134/s0003683816020034